Z-Project
2024
Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids
Jean-Philippe Auger, Max Zimmermann, Maria Faas, Ulrich Stifel, David Chambers, Brenda Krishnacoumar, R Verena Taudte, Charlotte Grund, Gitta Erdmann, Carina Scholtysek, Stefan Uderhardt, Oumaima Ben Brahim, Mónica Pascual Maté, Cornelia Stoll, Martin Böttcher, Katrin Palumbo-Zerr, Matthew S J Mangan, Maria Dzamukova, Markus Kieler, Melanie Hofmann, Stephan Blüml, Gernot Schabbauer, Dimitrios Mougiakakos, Uwe Sonnewald, Fabian Hartmann, David Simon, Arnd Kleyer, Anika Grüneboom, Susetta Finotto, Eicke Latz, Jörg Hofmann, Georg Schett, Jan Tuckermann, Gerhard Krönke
2023:
Enhancing student understanding of rheumatic disease pathologies through augmented reality: findings from a multicentre trial
Alexander Pfeil, Philipp Klemm, Axel J Hueber, Tobias Hoffmann, Tobias Weise, Peter Oelzner, Stefan Knop, Ulf Müller-Ladner, Uwe Lange, Gunter Wolf, Georg Schett, David Simon, Arnd Kleyer
Imaging in inflammatory arthritis: progress towards precision medicine
Ioanna Minopoulou, Arnd Kleyer, Melek Yalcin-Mutlu, Filippo Fagni, Stefan Kemenes, Christian Schmidkonz, Armin Atzinger, Milena Pachowsky, Klaus Engel, Lukas Folle, Frank Roemer, Maximilian Waldner, Maria-Antonietta D’Agostino, Georg Schett, David Simon
Healthcare utilization and unmet needs of patients with antisynthetase syndrome: An international patient survey
M Weiss, M T Holzer, F Muehlensiepen, Y Ignatyev, C Fiehn, J Bauhammer, J Schmidt, S Schlüter, A Dihkan, D Scheibner, U Schneider, L Valor-Mendez, G Corte, L Gupta, H Chinoy, I Lundberg, L Cavagna, J H W Distler, G Schett, J Knitza
Rescue therapy of antisynthetase syndrome with CD19-targeted CAR-T-cells after failure of several B cell depleting antibodies
Jule Taubmann, Johannes Knitza, Fabian Müller, Simon Völkl, Michael Aigner, Arnd Kleyer, Regina Gary, Sascha Kretschmann, Sebastian Boeltz, Armin Atzinger, Torsten Kuwert, Frank Roemer, Michael Uder, Andreas Mackensen, Georg Schett
DeepNAPSI multi-reader nail psoriasis prediction using deep learning
Lukas Folle, Pauline Fenzl, Filippo Fagni, Mareike Thies, Vincent Christlein, Christine Meder, David Simon, Ioanna Minnopoulou, Michael Sticherling, Georg Schett, Andreas Maier, Arnd Kleyer
An AI-Powered Clinical Decision Support System to Predict Flares in Rheumatoid Arthritis: A Pilot Study
Hannah Labinsky, Dubravka Ukalovic, Fabian Hartmann, Vanessa Runft, André Wichmann, Jan Jakubcik, Kira Gambel, Katharina Otani, Harriet Morf, Jule Taubmann, Filippo Fagni, Arnd Kleyer, David Simon, Georg Schett, Matthias Reichert and Johannes Knitza
2022:
Real-world usage of digital health applications (DiGA) in rheumatology: results from a German patient survey
Hannah Labinsky, Latika Gupta, Maria Gabriella Raimondo, Georg Schett, Johannes Knitza
Digitally supported shared decision-making and treat-to-target in rheumatology: a qualitative study embedded in a multicenter randomized controlled trial
Felix Muehlensiepen, Susann May, Katharina Hadaschik, Nicolas Vuillerme, Martin Heinze, Manuel Grahammer, Hannah Labinsky, Sebastian Boeltz, Jacqueline Detert, Jana Petersen, Gerhard Krönke , Georg Schett, Johannes Knitza
Advanced neural networks for classification of MRI in psoriatic arthritis, seronegative, and seropositive rheumatoid arthritis
Lukas Folle, Sara Bayat, Arnd Kleyer, Filippo Fagni, Lorenz A Kapsner, Maja Schlereth, Timo Meinderink, Katharina Breininger, Koray Tascilar, Gerhard Krönke, Michael Uder, Michael Sticherling, Sebastian Bickelhaupt, Georg Schett, Andreas Maier, Frank Roemer, David Simon
Comparison of physician and artificial intelligence-based symptom checker diagnostic accuracy
Markus Gräf, Johannes Knitza, Jan Leipe, Martin Krusche, Martin Welcker, Sebastian Kuhn, Johanna Mucke, Axel J Hueber, Johannes Hornig, Philipp Klemm, Stefan Kleinert, Peer Aries, Nicolas Vuillerme, David Simon, Arnd Kleyer, Georg Schett, Johanna Callhoff
Remote self-collection of capillary blood using upper arm devices for autoantibody analysis in patients with immune-mediated inflammatory rheumatic diseases
Joshua Zarbl, Ekaterina Eimer, Camilla Gigg, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch, Arnd Kleyer, David Simon, Sebastian Boeltz, Martin Krusche, Johanna Mucke, Felix Muehlensiepen, Nicolas Vuillerme, Gerhard Krönke, Georg Schett, Johannes Knitza
Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study
David Simon, Koray Tascilar, Filippo Fagni, Arnd Kleyer, Gerhard Krönke, Christine Meder, Peter Dietrich, Till Orlemann, Johanna Mößner, Jule Taubmann, Melek Yalcin Mutlu, Johannes Knitza, Stephan Kemenes, Anna-Maria Liphardt, Verena Schönau, Daniela Bohr, Louis Schuster, Fabian Hartmann, Ioanna Minopoulou, Moritz Leppkes, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Axel J Hueber, Karin Manger, Bernhard Manger, Raja Atreya, Carola Berking, Michael Sticherling, Markus F Neurath, Georg Schett
Neutralizing monoclonal antibodies against SARS-CoV-2 for COVID-19 pneumonia in a rituximab treated patient with systemic sclerosis-A case report and literature review
Melek Yalcin Mutlu, Jule Taubmann, Jochen Wacker, Koray Tascilar, Filippo Fagni, Maximilian Gerner, Daniel Klett, Georg Schett, Bernhard Manger, David Simon
Cinematic rendering in rheumatic diseases-Photorealistic depiction of pathologies improves disease understanding for patients
Milena L Pachowsky, Harriet Morf, David Simon, Verena Schönau, Larissa Valor-Mendez, Johannes Knitza, Filippo Fagni, Klaus Engel, Michael Uder, Axel Hueber, Christian Schmidkonz, Georg Schett, Arnd Kleyer
Machine learning-based improvement of an online rheumatology referral and triage system
Johannes Knitza, Lena Janousek, Felix Kluge, Cay Benedikt von der Decken, Stefan Kleinert, Wolfgang Vorbrüggen, Arnd Kleyer, David Simon, Axel J Hueber, Felix Muehlensiepen, Nicolas Vuillerme, Georg Schett, Bjoern M Eskofier, Martin Welcker, Peter Bartz-Bazzanella
Non-invasive metabolic profiling of inflammation in joints and entheses by multispectral optoacoustic tomography
Koray Tascilar, Filippo Fagni, Arnd Kleyer, Sara Bayat, Robert Heidemann, Florian Steiger, Gerhard Krönke, Daniela Bohr, Andreas Ramming, Fabian Hartmann, Daniel Klett, Anna Federle, Adrian P Regensburger, Alexandra L Wagner, Ferdinand Knieling, Markus F Neurath, Georg Schett, Maximilian Waldner, David Simon
Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial
Johannes Knitza, Koray Tascilar, Nicolas Vuillerme, Ekaterina Eimer, Paul Matusewicz, Giulia Corte, Louis Schuster, Timothée Aubourg, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch , Arnd Kleyer, Sebastian Boeltz, Axel J Hueber, Gerhard Krönke, Georg Schett, David Simon
Impact of Cytokine Inhibitor Therapy on the Prevalence, Seroconversion Rate, and Longevity of the Humoral Immune Response Against SARS-CoV-2 in an Unvaccinated Cohort
David Simon, Koray Tascilar, Arnd Kleyer, Filippo Fagni, Gerhard Krönke, Christine Meder, Peter Dietrich, Till Orlemann, Thorsten Kliem, Johanna Mößner, Anna-Maria Liphardt, Verena Schönau, Daniela Bohr, Louis Schuster, Fabian Hartmann, Moritz Leppkes, Andreas Ramming, Milena Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Axel J Hueber, Karin Manger, Bernhard Manger, Raja Atreya, Carola Berking, Michael Sticherling, Markus F Neurath, Georg Schett
Deep Learning-Based Classification of Inflammatory Arthritis by Identification of Joint Shape Patterns—How Neural Networks Can Tell Us Where to “Deep Dive” Clinically
Lukas Folle, David Simon, Koray Tascilar, Gerhard Krönke, Anna-Maria Liphardt, Andreas Maier, Georg Schett and Arnd Kleyer
TELERA—Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial
Johanna Mucke, Johannes Knitza, Felix Muehlensiepen, Manuel Grahammer, Ramona Stenzel, David Simon, Arnd Kleyer, Gerhard Krönke, Charlotte Sharp, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch, Nicolas Vuillerme, Georg Schett, Ann-Christin Pecherand, Martin Krusche
2021:
Efficacy and safety of SARS-CoV-2 revaccination in non-responders with immune-mediated inflammatory disease
David Simon, Koray Tascilar, Filippo Fagni, Katja Schmidt, Gerhard Krönke, Arnd Kleyer, Andreas Ramming, Verena Schoenau, Daniela Bohr, Johannes Knitza, Thomas Harrer, Karin Manger, Bernhard Manger, Georg Schett
Performance of a Handheld Ultrasound Device to Assess Articular and Periarticular Pathologies in Patients with Inflammatory Arthritis
Giulia Corte, Sara Bayat, Koray Tascilar, Larissa Valor-Mendez, Louis Schuster, Johannes Knitza, Filippo Fagni, Georg Schett, Arnd Kleyer, David Simon
Biomechanical stress in the context of competitive sports training triggers enthesitis
Simon D, Kleyer A, Bayat S, Knitza J, Valor-Mendez L, Schweiger M, Schett G, Tascilar K, Hueber AJ
SARS-CoV-2 vaccination responses in untreated, conventionally treated and anticytokine-treated patients with immune-mediated inflammatory diseases
David Simon, Koray Tascilar, Filippo Fagni, Gerhard Krönke, Arnd Kleyer, Christine Meder, Raja Atreya, Moritz Leppkes, Andreas E Kremer, Andreas Ramming, Milena L Pachowsky, Florian Schuch, Monika Ronneberger, Stefan Kleinert, Axel J Hueber, Karin Manger, Bernhard Manger, Carola Berking, Michael Sticherling, Markus F Neurath, and Georg Schett
Advanced machine learning for predicting individual risk of flares in rheumatoid arthritis patients tapering biologic drugs
Asmir Vodencarevic, Koray Tascilar, Fabian Hartmann, Michaela Reiser, Axel J Hueber, Judith Haschka, Sara Bayat, Timo Meinderink, Johannes Knitza, Larissa Mendez, Melanie Hagen, Gerhard Krönke , Jürgen Rech, Bernhard Manger, Arnd Kleyer, Marcus Zimmermann-Rittereiser, Georg Schett, David Simon, RETRO study group
2020:
Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion
Simon D, Tascilar K, Krönke G, Kleyer A, Zaiss MM, Heppt F, Meder C, Atreya R, Klenske E, Dietrich P, Abdullah A, Kliem T, Corte G, Morf H, Leppkes M, Kremer AE, Ramming A, Pachowsky M, Schuch F, Ronneberger M, Kleinert S, Maier C, Hueber AJ, Manger K, Manger B, Berking C, Tenbusch M, Überla K, Sticherling M, Neurath MF, Schett G.
Bone microstructure and volumetric bone mineral density in patients with hyperuricemia with and without Psoriasis
Mobile Health Usage, Preferences, Barriers, and eHealth Literacy in Rheumatology: Patient Survey Study
Knitza J, Simon D, Lambrecht A, Raab C, Tascilar K, Hagen M, Kleyer A, Bayat S, Derungs A, Amft O, Schett G and Hueber AJ.
Bone Mass, Bone Microstructure and Biomechanics in Patients with Hand Osteoarthritis
A set of serum markers detecting systemic inflammation in psoriatic skin, entheseal, and joint disease in the absence of C-reactive protein and its link to clinical disease manifestations
Sokolova M, Simon D, Nas K, Zaiss MM, Luo Y, Zhao Y, Rech J and Schett G.
2019:
Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study
Kampylafka E, Simon D, d’Oliveira I, Linz C, Lerchen V, Englbrecht M, Rech J, Arnd Kleyer A, Sticherling M, Schett G, Hueber AJ.
Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients
Simon D, Kleyer A, Bayat S, Tascilar K, Kampylafka E, Meinderink T, Schuster L, Petrov R, Liphardt A-M, Rech J, Schett G, Hueber AJ.
The ageing joint-standard age- and sex-related values of bone erosions and osteophytes in the hand joints of healthy individuals